Umbilical Cord Pseudocyst and Aneuploidy
Ref	Findings in addition to pseudocyst	Karyotype
(1) (2) (3) (3) (4) (5) (5) (6) (7) (8) (9) (9) (10) (11)	Isolated cyst and edema Isolated cyst at 22 weeks Posterior fossa cyst and IUGR IUGR Cystic cord mass Hydrops, Single umbilical artery Omphalocele 8 cases/isolated cysts in 1st trimester Holoprosencephaly, single umbilical artery VATER type abnormalities IUGR, pericardial effusion, abnormal hands + feet, abnormal head/body proportion Two cord cysts IUGR, microcephaly, ventriculomegaly, micropthalmia, cleft palate, CHD, polydactyly. 13 cases: 10 had prenatal karyotyping. Multiple anomalies, polyhydramnios. Multiple anomalies, polyhydramnios. Hydrops, polyhydramnios. Cystic hygroma, hydrops Omphalocele Acrania	Normal Normal Trisomy 18 Trisomy 18 Normal Trisomy 18 Trisomy 18 Normal Trisomy 13 Normal Trisomy 18 Normal Trisomy 13 Trisomy 18 (5) Trisomy 13 (1) 46XX,invins(18;21) 46,XY (1) 46,XY (1) 46,XX (1)

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